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Job Description

Scientist / Senior Scientist – 3D Genome & NGS Assay Development // Oxford

You are a creative, hands-on assay developer who loves to tinker with protocols, optimise them, and build NGS-based methods that genuinely move science forward. You think deeply about why assays work, when to deviate from a protocol, and how to adapt methods to new cell types and biological questions.

You want to be in a small, high-impact biotech environment where your work directly unblocks an R&D pipeline, rather than adding another incremental dataset to a queue of papers. You’re motivated by impact, pace, and the opportunity to shape how a platform evolves.

We’re partnering with an incredibly exciting, Oxford-based biotech operating at the forefront of 3D genome and non-coding genomics, they are operating assays at the forefront of Biotechnology at scale, a true innovator in this space. Their discovery engine integrates novel assays, deep genomics and high-resolution chromatin biology to uncover gene-regulatory mechanisms that conventional approaches miss.

You will join a core 3D genome assay team. Your work will directly increase throughput, accelerate assay optimisation, and enable expansion into new disease areas and primary cell systems.

THE ROLE

You will:

Develop, refine and optimise 3D genome and NGS-based assays (e.g. ATAC‑seq, ChIP‑seq, RNA‑seq and conceptually related methods) Design and execute experiments to expand assays into new primary cell types and disease-relevant systems Work closely with a Principal Scientist to prioritise work, expanding the platform’s capabilities Collaborate with bioinformatics and biology colleagues to ensure that assay design and data output align with downstream analysis and decision-making

ABOUT YOU

Background in gene regulation, chromatin biology, epigenetics or closely related field Strong, hands-on experience in NGS assay development (e.g. ATAC‑seq, ChIP‑seq, RNA‑seq or similar)s) Bonus: experience with any 3D genome assay (e.g. Hi‑C, Capture‑C or related technologies) Enjoy working in an experimental, innovation-driven environment and taking ownership of your work

LOGISTICS

Title: Scientist or Senior Scientist (flexible, depending on experience) Location: Oxford, lab-based

If you’re excited by the idea of building and refining assays at the heart of a 3D genome discovery platform, Apply Now!

If you are interested in applying for this job please press the Apply Button and follow the application process. Energy Jobline wishes you the very best of luck in your next career move.