Confidential Job Description

Position: Principal Investigator

Location: Yorkshire, UK

Overview

We are representing a rapidly expanding, UK-based clinical research organization seeking an experienced and motivated Principal Investigator (PI) to lead clinical trials at a Yorkshire site. This is an excellent opportunity for a medically qualified professional to take on a leadership role within a high-growth environment focused on delivering high-quality, patient-centric research.

Key Responsibilities

• Act as Principal Investigator on a range of clinical trials across multiple therapeutic areas
• Ensure all studies are conducted in compliance with ICH-GCP, regulatory requirements, and study protocols
• Provide clinical oversight and leadership to the research team, including Sub-Investigators and site staff
• Safeguard patient safety, wellbeing, and informed consent processes at all times
• Support and contribute to patient recruitment strategies to meet and exceed enrolment targets
• Maintain accurate and complete source documentation and data integrity
• Collaborate with sponsors, CROs, and internal stakeholders to ensure successful study delivery
• Participate in monitoring visits, audits, and inspections
• Contribute to continuous improvement initiatives and support the growth of the site

Key Skills & Experience

• GMC-registered medical doctor with a licence to practise in the UK
• Previous experience as a Principal Investigator or Sub-Investigator in clinical research
• Strong understanding of ICH-GCP guidelines and regulatory frameworks
• Demonstrated ability to lead clinical teams and manage multiple studies
• Excellent communication and stakeholder management skills
• Passion for clinical research and improving patient access to innovative treatments

What’s on Offer

• Clear and structured career progression pathway to Associate Medical Director
• Opportunity to join a high-growth organization with expanding UK footprint
• A collaborative, supportive, and dynamic working environment
• Competitive salary with annual pay reviews