University Hospitals Sussex NHS Foundation Trust is seeking two motivated, flexible and resilient Lead Clinical Nurse Specialists to join and lead our Acute Oncology (AO) services across our sites at the Royal Sussex County Hospital, Princess Royal Hospital, Worthing Hospital and St Richard's Hospital.

As Lead CNS, you will provide strategic, clinical and operational leadership for the Acute Oncology, Cancer of Unknown Primary (CUP) and Immunotherapy Toxicity (OTIS) services. You will lead and line‑manage the AO teams across RSCH/PRH or WGH/SRH, working collaboratively with senior leadership to develop high‑quality, responsive services aligned with national recommendations.

Working at an advanced practice level for 50% of your role, you will act as an expert resource across Oncology, demonstrating in‑depth knowledge of cancer, systemic treatments and associated toxicities. You will provide specialist clinical leadership for patients presenting acutely unwell due to cancer or treatment, those with suspected new cancer diagnoses, and patients with CUP, ensuring robust support for individuals and families throughout their pathway, including post‑MDT discussions.

You will join a dynamic, supportive and forward‑thinking Cancer Division committed to delivering consistent standards of care and collaborative working across the Trust.

Main duties of the job

• Leading AO service development across designated sites to ensure consistent, high‑quality care.
• Providing expert clinical leadership to deliver individualised, patient‑centred acute oncology care in inpatient and outpatient settings.
• Strengthening education and training for multidisciplinary teams in AO, CUP and immunotherapy toxicity management.