4basebio (AIM: 4BB) is a Cambridge-based biotechnology company pioneering the use of synthetic DNA to enable next-generation therapeutics and vaccines. Through its proprietary enzymatic DNA synthesis platform, 4basebio produces GMP-grade synthetic DNA and mRNA with superior speed, purity, and scalability, overcoming the limitations of plasmid-based systems. The company offers application-specific DNA constructs tailored to the diverse needs of gene therapies, genome editing, mRNA production, and DNA vaccines, helping partners accelerate proof-of-concept studies and reach clinical milestones more efficiently while maintaining the highest standards of safety and quality.

The Commercial Operations Manager is responsible for overseeing and optimizing commercial operations, building structure, improving efficiency, and turning revenue strategy into operational reality.

Key Responsibilities:

• Own and optimise the CRM, including pipeline architecture, deal stages, workflows, automation, and reporting
• Design and evolve pipeline & forecast analytics, applying data-driven decision to drive measurable improvements in progression, growth, forecast accuracy, and pipeline sufficiency
• Build repeatable dashboards and automated frameworks that reduce manual effort and enable self-service insights for revenue leaders
• Partner cross-functionally with Sales, Customer Success, Marketing, Partnerships, and Finance to identify conversion gaps, execution risks, and pipeline health issues
• Support renewals and churn visibility work by helping define baselines, directional risk indicators, and forecasting inputs grounded in clear assumptions and consistent definitions.
• Translate analytical outputs into concise narratives, recommendations, and trade-offs for executive and leadership audiences to support forecast and pipeline cadences
• Drive standardization of inputs, outputs, definitions, and processes across regions and functions to improve consistency, data quality, and operational efficiency

Required Experience

• Bachelor's degree in Business, Computer Science, or related field
• 5+ years of experience in sales/commercial operations, CRM and Marketing Automation administration (Hubspot, Salesforce, Klient, etc)
• Proven track record building and managing a multi-tool sales technology stack
• Strong background in project management and process improvement

Skills

• Strategic thinking and business acumen
• Advanced technical knowledge of digital platforms and technologies
• Excellent leadership and team management abilities
• Strong analytical and problem-solving skills
• Outstanding communication and stakeholder management
• Experience in the life science field, preferred

Working Conditions

• Full-time position
• UK based, but will explore remote position for the right candidate
• May require occasional travel
• Fast-paced environment with changing priorities

What we offer:

Competitive salary, performance-based bonus structure; travel and expense allowance and a comprehensive benefits package