Analytical Scientist (Biotechnology / LNP & Lipid Analytics) in Didcot
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Job Description
NeoVac is building a new groundbreaking LNP platform to deliver better mRNA vaccines and treatments for various diseases. At NeoVac, we envision a world where mRNA vaccines and treatments are available to everyone and everywhere.
A new opportunity has arisen for a full-time permanent for Analytical Scientist. As an Analytical Scientist, you will be responsible for the development, optimisation, and validation of analytical methods to characterise lipids, PEG-polymers, nanoparticle components, process intermediates, and final drug substances.
You will work closely with formulation chemistry, RNA teams, and manufacturing partners to support drug development from discovery through early GMP stages.
This role requires strong laboratory autonomy, problem-solving capabilities, and a passion for high-quality data.
Responsibilities
•\tDevelop, optimise, and validate analytical methods for lipids, polymers, and nanoparticle components using: HPLC-CAD, HPLC-UV, LC-MS.
•\tPerform structural and compositional profiling of PEG-lipids, ionisable lipids, and excipients.
•\tExecute method validation according to ICH Q2 and support transition into cGMP workflows.
•\tConduct routine and non-routine analyses: assay, related impurities, stability studies and Endotoxin analysis.
•\tIndependently troubleshoot analytical methods and instruments.
•\tInterpret data, prepare reports, and present results to cross-functional teams.
•\tSupport external CROs, CDMOs, and GMP partners as needed.
•\tContribute to building analytical capability in a growing biotech environment, including SOPs, workflows, and instrument best practices.
Qualifications & Experience
•\tMaster’s degree (MSc or higher) in Chemistry, Analytical Chemistry, Pharmaceutical Sciences or related field.
•\t3+ years hands-on experience with HPLC in industry (pharma/biotech ).
•\tDemonstrated proficiency with HPLC-CAD (strongly ).
•\tHands-on experience with LC-MS for lipid or polymer analysis.
•\tProven track record of method development (minimum 3–5 methods).
•\tExperience with cGMP method validation (at least 2 methods independently validated).
•\tPrior experience working in a GMP or cGMP analytical lab.
•\tStrong practical skills, autonomy, and troubleshooting abilities.
•\tExcellent documentation practices; familiarity with ICH Q2, Q14, and relevant regulatory guidelines.
•\tAbility to thrive in a fast-paced, collaborative start-up environment.
Required Skills
•\tExperience with lipid nanoparticles (LNPs), PEG-lipids, polymers, or novel excipients.
•\tExperience with charged aerosol detection optimisation.
•\tKnowledge of DSC, Capillary Electrophoresis (CE), and Bacterial Endotoxin analysis.
•\tExperience drafting SOPs, method protocols, validation reports.
•\tFamiliarity with raw material qualification and release testing.
If you are interested in applying for this job please press the Apply Button and follow the application process. Energy Jobline wishes you the very best of luck in your next career move.
- Location:
- Didcot
- Job Type:
- FullTime
- Category:
- Analytics, Biotechnology, Scientist, Science